[Supernumerary nostril]. / Tercera ventana nasal.

Supernumerary nostril is an extremely rare congenital anomaly as a result of aberrant embryological development. Frequently it leads to a narrow cavity; in the end, opening into the nearest nasal cavity or just stops blindly after a short course. It can appear isolated or in association with other anomalies. Treatment is always surgical. We present a case of a triple nostril, associated to a congenital auricular hypoplasia and we also review the existing literature.

Tercera ventana nasal / Supernumerary nostril

La tercera ventana nasal es una anomalía congénita muy rara que resulta de un desarrollo embriológico aberrante. La mayor parte de las veces se continúa hacia atrás en una cavidad nasal que a su vez puede comunicar con la fosa natural más cercana o acabar en fondo de saco. Puede aparecer aislada o asociada a otras anomalías. El tratamiento es quirúrgico. Presentamos un caso de tercera ventana nasal con hipoplasia de pabellón auricular derecho asociada, revisando la literatura existente (AU)

Supernumerary nostril is an extremely rare congenital anomaly as a result of aberrant embryological development. Frequently it leads to a narrow cavity; in the end, opening into the nearest nasal cavity or just stops blindly after a short course. It can appear isolated or in association with other anomalies. Treatment is always surgical. We present a case of a triple nostril, associated to a congenital auricular hypoplasia and we also review the existing literature (AU)

[Subjective satisfaction among patients with endoscopic surgery of paranasal sinuses]. / Satisfacción subjetiva en pacientes intervenidos de cirugía endoscópica nasosinusal. Nuestra experiencia.

The analysis of the subjective satisfaction degree in patients following endoscopic sinus surgery is a very important data to be studied in a ENT Hospital Departments. In a very high percentage of cases, the result was good or very good. No cases were reported as worse. Statistically the relationship between non-existence of post surgery complications and the rate of symptoms of smaller importance was logical. We would like to point out the importance in the meaningful association between the high degree of satisfaction with the presence of significant postoperative endoscopic findings.

Autoinjerto subcutáneo de cartílago neosintetizado utilizando el polímero ethisorb® en conejos / Subcutaneous autograft of neo-synthetic cartilage using the ethisorb® polymer in rabbits

Realizamos un autotransplante subcutáneo, en animales inmunocompetentes (24 conejos), de cartílago extraído del pabellón auricular, tratado mediante técnicas de ingeniería tisular y embebidos en un polímero reabsorbible (Ethisorb®) que le sirve de sostén. Encontramos que se produce un cartílago de buena calidad, con la expresión del colágeno tipo II y sin observar fenómenos de rechazo del injerto (AU)

We perform a subcutaneous autograft, in animals with preserved immunity (24 rabbits), of cartilage taken from the auricle, treated with tissue engineering thecnics and embeded in a reabsorbable polimer (Ethisorb) that acts as base. We observed a good quality cartilage with the expression of collagen type II and without graft rejection phenomenon (AU)

[Subcutaneous autograft with newly synthesized cartilage using ethisorb polymer in rabbits]. / Autoinjerto subcutáneo de cartílago neosintetizado utilizando el polímero ethisorb en conejos.

We perform a subcutaneous autograft, in animals with preserved immunity (24 rabbits), of cartilage taken from the auricle, treated with tissue engineering thecnics and embeded in a reabsorbable polimer (Ethisorb) that acts as base. We observed a good quality cartilage with the expression of collagen type II and without graft rejection phenomenon.

[Familial mixed hearing loss associated with X chromosome and stapedial gusher]. / Hipoacusia mixta familiar asociada al cromosoma X con gusher estapedial.

Perilymphatic and/or CSF loss through the oval window during stapedectomy is called a gusher. This rare disorder is associated with X-linked progressive mixed hearing loss. It is related with mutations in the POU3F4 gene at locus DFN3 on Xq21. Our study of the cases seen in our department yielded information and clinical and radiological findings that could be useful for the clinical management, early diagnosis, and prevention of erroneous therapeutic indications.

[Tissue engineering of cartilagenous tissue. Vital cryopreservation]. / Ingeniería tisular de tejido cartilaginoso. Criopreservación vital.

The characteristics of in vitro synthesized cartilage tissue using tissue engineering techniques before and after cryopreservation are described. We determined cell survival, growth of extracellular matrix (collagen and proteoglycan) using a computer analysis system, and characterized the cell phenotype with a monoclonal antibody specific for collagen type II. Chondrocytes maintained a differentiated phenotype with collagen and proteoglycan synthesis before and after cryopreservation.